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CTPB

p300 HAT activator
 
ALX-420-033-M001 1 mg 48.00 USD
 
ALX-420-033-M005 5 mg 145.00 USD
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Potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.

Product Specification

Alternative Name:N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide
 
Formula:C31H43ClF3NO2
 
MW:554.1
 
CAS:586976-24-1
 
Purity:≥97% (1H-NMR)
 
Identity:Determined by NMR.
 
Appearance:White to off-white crystalline solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
420-033
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420-033

Product Literature References

Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy: K. Mantelingu, et al.; J. Phys. Chem. B. 111, 4527 (2007), Abstract;

General Literature References

Small molecule modulators of histone acetyltransferase p300: K. Balasubramanyam, et al.; J. Biol. Chem. 278, 19134 (2003), Abstract;

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