Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Teniposide

Topoisomerase II inhibitor
 
ALX-400-053-M025 25 mg 62.00 USD
 
ALX-400-053-M100 100 mg 184.00 USD
Do you need bulk/larger quantities?
 
Glycoside-derivative of podophyllotoxin. Has cytostatic effect. Inhibits topoisomerase II. Induces apoptosis.

Product Specification

Alternative Name:(5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]furo[3’,4’:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 4’-Demethylepipodophyllotoxin-β-D-thenylidine glucoside
 
Formula:C32H32O13S
 
MW:656.7
 
Source:Semisynthetic derivative of podophyllotoxin.
 
CAS:29767-20-2
 
MI:14: 9145
 
Purity:≥97% (HPLC)
 
Identity:Determined by IR.
 
Appearance:White to off-white powder.
 
Solubility:Soluble in acetone or dimethyl formamide; slightly soluble in methanol; insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
400-053
Please mouse over
400-053

Product Literature References

Regulation of hepatic cholesteryl ester transfer protein expression and reverse cholesterol transport by inhibition of DNA topoisomerase II: M. Liu, et al.; J. Biol. Chem. 290, 14418 (2015), Application(s): Cell Culture, Injection into mice, Abstract; Full Text
Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma: J. Li, et al.; World J. Surg. Oncol. 4, 41 (2006), Abstract; Full Text
Topoisomerase II as a target of VM-26 and 4’-(9-acridinylamino)methanesulfon-m-aniside in atypical multidrug resistant human small cell lung carcinoma cells: S. de Jong, et al.; Cancer Res. 53, 1064 (1993), Abstract; Full Text
Human cytochrome P450 metabolism of teniposide and etoposide: M.V. Relling, et al.; J. Pharmacol. Exp. Ther. 261, 491 (1992), Abstract;
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage: W. Ross, et al.; Cancer Res. 44, 5857 (1984), Abstract; Full Text

Related Products

Podophyllotoxin 

Topoisomerase inhibitor
518-28-5, Isolated from Podophyllum peltatum., ≥98% (HPLC) | Print as PDF
 
ALX-630-086-M100 100 mg 40.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Topoisomerase
By biological activity:
Topoisomerase Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,