Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Nimustine . hydrochloride

DNA alkylating agent
 
ALX-400-052-M250 250 mg Inquire for pricing
Do you need bulk/larger quantities?
 
DNA alkylator and cross-linker. Anticancer agent used to treat malignant glioma. Cardiovascular teratogenicity was studied in rat fetuses.

Product Specification

Alternative Name:1-(4-Amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea . HCl, ACNU . HCl
 
Formula:C9H13ClN6O2 . HCl
 
MW:272.7 . 36.5
 
Source:Synthetic.
 
CAS:55661-38-6
 
MI:14: 6553
 
RTECS:YR8450000
 
Purity:≥98% (HPLC)
 
Identity:Determined by IR.
 
Appearance:White to light yellow crystalline solid.
 
Solubility:Soluble in methanol or water; slightly soluble in 100% ethanol or n-butanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from moisture.
 
400-052
Please mouse over
400-052

Product Literature References

Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: an immunohistochemical analysis: T. Anda, et al.; Neurol. Res. 25, 241 (2003), Abstract;
Comparative cytotoxicity of carmustine (BCNU), nimustine (ACNU) and elmustine (HeCNU) after depletion of O6-alkylguanine-DNA alkyltransferase (O6-AGT): T.R. Buch & W.J. Zeller; Anticancer Res. 22, 697 (2002), Abstract;
Effects of combination chemotherapy with biscoclaurine-derived alkaloid (Cepharanthine) and nimustine hydrochloride on malignant glioma cell lines: K. Kono, et al.; J. Neurooncol. 56, 101 (2002), Abstract;
Cardiovascular anomalies produced by nimustine hydrochloride in the rat fetus: S. Miyagawa, et al.; Teratology 38, 553 (1988), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,