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Virustomycin A

Antiviral agent
 
ALX-380-323-M001 1 mg 109.00 USD
 
ALX-380-323-M005 5 mg 434.00 USD
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18-membered macrolide. Active against trichomonads and various RNA and DNA viruses. Weakly active against some fungi. Has antitrypanosomal activity.

Product Specification

Alternative Name:23-O-De(4-O-aminocarbonyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-23-O-[4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,4-dioxo-2-butenyl]concanamycin A
 
Formula:C48H71NO14
 
MW:886.1
 
Source:Isolated from Streptomyces sp. AM-2604.
 
CAS:84777-85-5
 
Purity:≥97% (HPLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in acetone, chloroform, 100% ethanol or methanol; insoluble in water or hexane.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Manufactured with courtesy strain from The Kitasato Institute.
 
alx-380-323
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Product Literature References

Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites: K. Otoguro, et al.; J. Antibiot. 61, 372 (2008), Abstract;
The mode of action of a novel 18-membered macrolide, virustomycin A (AM-2604 A), on Trichomonas foetus: S. Omura, et al. ; J. Antibiot. 36, 1755 (1983), Abstract; Full Text
The structure of virustomycin A: S. Omura, et al.; J. Antibiot. 36, 1783 (1983), Abstract;
AM-2604 A, a new antiviral antibiotic produced by a strain of Streptomyces: S. Omura, et al.; J. Antibiot. 35, 1632 (1982), Abstract; Full Text

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