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Niphimycin

Antifungal antibiotic
 
ALX-380-307-C100 100 µg 830.00 USD
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Antifungal antibiotic. The fungicidal activity appears to result from membrane damage and enhanced oxidative stress.

Product Specification

Alternative Name:Scopafungin
 
Formula:C59H103N3O18
 
MW:1142.5
 
Source:Isolated from Streptomyces sp.
 
CAS:11056-18-1
 
Purity:≥90%
 
Appearance:Colorless powder.
 
Solubility:Soluble in methanol or DMSO.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
380-307
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380-307

Product Literature References

Synergistic combination of direct plasma membrane damage and oxidative stress as a cause of antifungal activity of polyol macrolide antibiotic niphimycin: K. Nakayama, et al.; J. Biosci. Bioeng. 94, 207 (2002), Abstract;
Structural Elucidation of Niphimycin, Part 3. Identity of Scopafungin and Niphimycin I. Position of the Malonyl Residue of Niphimycin and Copiamycin: P. Gassman, et al.; Helv. Chim. Acta 67, 696 (1984), Abstract;
On the Structure Elucidation of Niphimycin, Part I. Purification and Characterization of the Niphimycins I and I; Degradation by Nitric Acid: L. Bassi, et al.; Helv. Chim. Acta 66, 92 (1983), Abstract;

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