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Prulifloxacin

Fluoroquinolone antibacterial agent
 
ALX-380-299-M250 250 mg 105.00 USD
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Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria.

Product Specification

Alternative Name:6-Fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid, NM441
 
Formula:C21H20FN3O6S
 
MW:461.5
 
CAS:123447-62-1
 
MI:14: 7908
 
Purity:≥98% (Assay)
 
Identity:Determined by IR.
 
Appearance:White to yellow crystalline solid.
 
Solubility:Slightly soluble in dimethyl formamide, 0.1M NaOH or glacial acetic acid; insoluble in water or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-299
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380-299

Product Literature References

Pharmacologic characteristics of prulifloxacin: M.G. Matera; Pulm. Pharmacol. Ther. 19, 20 (2006), Abstract;
Prulifloxacin: a new antibacterial fluoroquinolone: G. Prats, et al.; Expert. Rev. Anti. Infect. Ther. 4, 27 (2006), (Review), Abstract;
Prulifloxacin: a new fluoroquinolone for the treatment of acute exacerbation of chronic bronchitis: M. Cazzola, et al.; Pulm. Pharmacol. Ther. 19, 30 (2006), Abstract;
Randomized, double-blind study of prulifloxacin versus ciprofloxacin in patients with acute exacerbations of chronic bronchitis: C. Grassi, et al.; Respiration 69, 217 (2002), Abstract; Full Text
Pharmacokinetics and safety of NM441, a new quinolone, in healthy male volunteers: M. Nakashima, et al.; J. Clin. Pharmacol. 34, 930 (1994), Abstract;
Studies on pyridonecarboxylic acids. 1. Synthesis and antibacterial evaluation of 7-substituted-6-halo-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3- carboxylic acids: J. Segawa, et al.; J. Med. Chem. 35, 4727 (1992), Abstract;
In vivo evaluation of NM441, a new thiazeto-quinoline derivative: M. Ozaki, et al.; Antimicrob. Agents Chemother. 35, 2496 (1991), Abstract; Full Text

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For Research Use Only. Not for use in diagnostic procedures.
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