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Streptomycin . sulfate

Antibiotic
 
ALX-380-277-G100 100 g 60.00 USD
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Antibiotic. Inhibits prokaryote protein synthesis. Binds to the S12 protein of the 30S ribosomal subunit. Effective against Gram-negative and Gram-positive bacteria. Mutation in rpsL (the gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Inactivated by aminoglycoside phosphotransferase.

Product Specification

Formula:C42H84N14O36S3
 
MW:1457.4
 
Source:Isolated from Streptomyces sp.
 
CAS:3810-74-0
 
MI:14: 8826
 
RTECS:WK4990000
 
Appearance:White to off-white powder.
 
Activity:Potency is >650 units/ml (on dry basis).
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-277
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380-277

Product Literature References

Streptomycin revisited: molecular action in the microbial cell: J.D. Kornder; Med. Hypotheses 58, 34 (2002), Abstract;
Mechanism of inhibition of ribosomes by streptomycin: J. Modolell & B.D. Davis; Nature 224, 345 (1969), Abstract;

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