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Kanamycin A . sulfate

Antibiotic. Apoptosis inducer.
 
ALX-380-275-G005 5 g 88.00 USD
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Aminoglycoside antibiotic. Binds to the 70S ribosomal subunit. Inhibits translocation and elicits miscoding. Interaction with ribosomes may be prevented by aminoglycoside modifying enzymes. Effective against Gram-negative and Gram-positive bacteria and mycoplasma.

Product Specification

Formula:C18H36N4O11 . H2SO4
 
MW:484.5 . 98.1
 
Source:Isolated from Streptomyces kanamyceticus.
 
CAS:25389-94-0
 
MI:14: 5281
 
RTECS:NZ3225030
 
Appearance:White to off-white crystalline powder.
 
Activity:Potency is >750µg/ml (on dry basis).
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-275
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380-275

Product Literature References

Antibiotic MICs and short time-killing against Helicobacter pylori: therapeutic potential of kanamycin: Y. Irie, et al.; J. Antimicrob. Chemother. 40, 235 (1997), Abstract;
Interaction of kanamycin A and kanamycin B with phospholipids: M.W. Yung & C. Green; J. Antibiot. 40, 862 (1987), Abstract;
Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production: K. Basak & S.K. Majumdar; Antimicrob. Agents Chemother. 4, 6 (1973), Abstract; Full Text
The total synthesis of kanamycin A: S. Umezawa, et al.; J. Antibiot. 21, 367 (1968), Abstract;
Infection of the protoplasts of Streptomyces kanamyceticus with deoxyribonucleic acid preparation from actinophage PK-66: M. Okanishi, et al.; J. Bacteriol. 92, 1850 (1966), Abstract; Full Text
Studies on Streptomyces kanamyceticus, producer of kanamycin: Y. Okami, et al.; J. Antibiot. 12, 252 (1959), Abstract;

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