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Colistin . sulfate

Antibiotic
 
ALX-380-272-M500 500 mg 105.00 USD
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Polymyxin antibiotic. Binds to lipids on the cell cytoplasmic membrane. Disrupts cell wall integrity. Effective against Gram-negative bacteria.

Product Specification

Alternative Name:Polymyxin E . sulfate
 
Source:Isolated from Bacillus colistinus.
 
CAS:1264-72-8
 
MI:14: 2479
 
RTECS:TR1500000
 
Purity Detail:Mixture of >30 compounds, primarily colistin A and B.
 
Appearance:White to off-white powder.
 
Activity:Potency is >19’900µg/ml (on dry basis).
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-272
Colistin B
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380-272

Product Literature References

Polymyxins: wisdom does not always come with age: Z. Kassamali, et al.; Clin. Infect. Dis. 57, 877 (2013), Abstract;
The clinical use of colistin in patients with cystic fibrosis: P. Beringer; Curr. Opin. Pulm. Med. 7, 434 (2001), (Review), Abstract;
Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram-negative bacteria: M.E. Evans, et al.; Ann. Pharmacother. 33, 960 (1999), (Review), Abstract;
Antibacterial action of colistin (polymyxin E) against Mycobacterium aurum: H.L. David & N. Rastogi; Antimicrob. Agents Chemother. 27, 701 (1985), Abstract; Full Text

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