Replaces Prod. #: BML-GR310
Antibiotic. Inhibits protein synthesis in eukaryotes by interfering with the translocation step. Induces apoptosis in tumor cell lines but can also delay or inhibit apoptosis induced by other agents. Widely used for selection of resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression. At 10µg/ml cycloheximide totally inhibits protein synthesis in mouse thymocytes.
Product Details
| Alternative Name: | Actidione, Naramycin A, 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide |
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| Formula: | C15H23NO4 |
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| MW: | 281.3 |
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| Source: | Isolated from Streptomyces griseus. |
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| CAS: | 66-81-9 |
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| MI: | 14: 2728 |
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| RTECS: | MA4375000 |
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| Purity: | ≥90% (HPLC) |
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| Appearance: | White to light yellow powder. |
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| Activity: | Potency is >900units/mg. |
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| Solubility: | Soluble in acetone, chloroform, ethanol, and methanol. Nearly insoluble in water. |
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| Shipping: | Ambient Temperature - Dangerous Good |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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