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Amikacin . disulfate

Antibiotic
 
ALX-380-266-G001 1 g 85.00 USD
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Aminoglycoside antibiotic. Effective against Gram-negative and Gram-positive bacteria.

Product Specification

Formula:C22H43N5O13 . 2H2SO4
 
MW:585.6 . 196.2
 
Source:Semisynthetic from kanamycin A (Prod. No. ALX-380-275).
 
CAS:39831-55-5
 
MI:14: 405
 
RTECS:WK1961200
 
Appearance:White to off-white crystalline powder.
 
Activity:Potency is 647-786µg/ml (on dry basis).
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-266
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380-266

Product Literature References

Biological transformation of kanamycin A to amikacin (BBK-8): L.M. Cappelletti & R. Spagnoli; J. Antibiot. 36, 328 (1983), Abstract;
Ototoxicity and pharmacokinetically determined dosages of amikacin in granulocytopenic cancer patients: F.J. Danhauer, et al.; Clin. Pharm. 1, 539 (1982), Abstract;
Aminoglycoside antibiotics. VII. Acute toxicity of aminoglycoside antibiotics: K. Fujisawa, et al.; J. Antibiot. 27, 677 (1974), Abstract;
Pharmacology of amikacin in humans: G.P. Bodey, et al.; Antimicrob. Agents Chemother. 5, 508 (1974), Abstract;
Comparative in vitro activity of three aminoglycosidic antibiotics: BB-K8, kanamycin, and gentamicin: P.K. Yu & J.A. Washington; Antimicrob. Agents Chemother. 4, 133 (1973), Abstract;
Comparative pharmacokinetics of BB-K8 and kanamycin in dogs and humans: B.E. Cabana & J.G. Taggart; Antimicrob. Agents Chemother. 3, 478 (1973), Abstract;
BB-K 8, a new semisynthetic aminoglycoside antibiotic: H. Kawaguchi, et al.; J. Antibiot. 25, 695 (1972), Abstract;

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Kanamycin . sulfate 

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Kanamycin A . sulfate 

Antibiotic. Apoptosis inducer.
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