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Aureothricin

RNA polymerase inhibitor
 
ALX-380-240-MC05 0.5 mg 309.00 USD
 
ALX-380-240-M001 1 mg 527.00 USD
 
ALX-380-240-M005 5 mg 1,470.00 USD
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Antibiotic. More hydrophobic analog of the antibiotic thiolutin (Prod. No. BML-CT107) with selective antitumor activity. Potent inhibitor of bacterial and yeast RNA polymerases and of fungal mannan and glucan formation.

Product Specification

Alternative Name:Propionylpyrrothione, Farcinicin
 
Formula:C9H10N2O2S2
 
MW:242.3
 
Source:Isolated from Streptomyces thioluteus.
 
CAS:574-95-8
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:Yellow to orange solid.
 
Solubility:Soluble in DMSO or dimethyl formamide; partially soluble in methanol or 100% ethanol; poorly soluble in water.
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:After reconstitution protect from light at -20°C.
 
380-240
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380-240

Product Literature References

Anticancer properties of dithiolopyrrolones: J.M. Webster, et al.; US Patent 6,020,360, (2000),
Studies on a common hydrolysis product of thiolutin and aureothricin: W.D. Celmer & I.A. Solomons; Antibiot. Annu. 622, (1953),

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Thiolutin 

RNA polymerase inhibitor
87-11-6, Isolated from Streptomyces luteosporeus, ≥95% (HPLC, TLC) | Print as PDF
 
BML-CT107-0001 1 mg 108.00 USD
 
BML-CT107-0005 5 mg 432.00 USD
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For Research Use Only. Not for use in diagnostic procedures.
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