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Trichostatin C

HDAC inhibitor
 
ALX-380-239-MC05 0.5 mg 359.00 USD
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Analog of trichostatin A (Prod. No. BML-GR309). Induces acetylation of histone H4. Shows antifungal activity.

Product Specification

Alternative Name:Antibiotic 145-A
 
Formula:C23H32N2O8
 
MW:464.5
 
Source:Isolated from Streptomyces sp. MST-AS5376.
 
CAS:68676-88-0
 
MI:14: 9649
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-239
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380-239

Product Literature References

Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation: T. Kohge, et al.; Biochem. Pharmacol. 56, 1359 (1998), Abstract;
Effects of trichostatins on differentiation of murine erythroleukemia cells: M. Yoshida, et al.; Cancer Res. 47, 3688 (1987), Abstract; Full Text
Trichostatin C, a glucopyranosyl hydroxamate: N. Tsuji and M. Kobayashi: N. Tsuji and M. Kobayashi; J. Antibiot. (Tokyo) 31, 939 (1978), Abstract;

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