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Isoapoptolidin

F-ATPase inhibitor
 
ALX-380-229-MC01 0.1 mg 347.00 USD
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Isomer of apoptolidin (Prod. No. ALX-380-207). In water an equilibrium mixture of apoptolidin:isoapoptolidin (~1.5:1) is formed within hours. Less active F0F1-ATPase inhibitor (IC50=17µM) than apoptolidin (IC50=0.7µM).

Product Specification

Formula:C58H96O21
 
MW:1129.4
 
Source:Isolated from Amycolatopsis sp. MST-AS5912.
 
CAS:476647-30-0
 
Purity:≥90% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-229
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380-229

Product Literature References

Isoapoptolidin: structure and activity of the ring-expanded isomer of apoptolidin: P.A. Wender, et al.; Org. Lett. 4, 3819 (2002), Abstract;
Toward a stable apoptolidin derivative: identification of isoapoptolidin and selective deglycosylation of apoptolidin: J.D. Pennington, et al.; Org. Lett. 4, 3823 (2002), Abstract;

Related Products

Apoptolidin 

F0F1-ATPase inhibitor
194874-06-1, Isolated from Amicolatopsis sp. MST-AS5912., ≥95% (HPLC) | Print as PDF
 
ALX-380-207-MC01 0.1 mg 283.00 USD
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