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Conglobatin

Immunosuppressant
 
ALX-380-225-MC05 0.5 mg 291.00 USD
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Macrolide antibiotic with an unusual dimeric macrolide dilactone structure. Exhibited immunosuppressant activity in a NFAT-dependent transcription assay (IC50=0.63µg/ml).

Product Specification

Formula:C28H38N2O6
 
MW:498.6
 
Source:Isolated from Streptomyces conglobatus MST-AS5530.
 
CAS:72263-05-9
 
RTECS:JG7521800
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
380-225
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380-225

Product Literature References

Simple aromatics identified with a NFAT-lacZ transcription assay for the detection of immunosuppressants: N.S. Burres, et al.; J. Antibiot. (Tokyo) 48, 380 (1995), Abstract;
Conglobatin, a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005: J.W. Westley, et al.; J. Antibiot. (Tokyo) 32, 874 (1979), Abstract;

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