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Asterric acid

VEGF inhibitor
 
ALX-380-208-M001 1 mg 202.00 USD
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Antibiotic. Inhibitor of vascular endothelial growth factor (VEGF).

Product Specification

Alternative Name:Dimethylosoic acid, TAN 1415A, WF 12880A
 
Formula:C17H16O8
 
MW:348.3
 
Source:Isolated from Aspergillus terreus MST-FP1370.
 
CAS:577-64-0
 
Purity:≥99% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
380-208
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380-208

Product Literature References

Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures: T. Boruta, et al.; Appl. Microbiol. Biotechnol. 100, 3009 (2016), Application(s): Cell culture, Abstract; Full Text
Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs: H.J. Lee, et al.; J. Antibiot. (Tokyo) 55, 552 (2002), Abstract;
Asterric acid, a new endothelin binding inhibitor: H. Ohashi, et al.; J. Antibiot. (Tokyo) 45, 1684 (1992), Abstract;
Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, questin and questinol: A. Mahmoodian & C.E. Stickings; Biochem. J. 92, 369 (1964), Abstract; Full Text

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