Ansatrienin B

Antitumor antibiotic



ALX-380-204-M001	1 mg	389.00 USD

Antitumor antibiotic, closely related to the cytotrienins. Displays potent anticancer activities. Significantly potentiates the action of several clinical antitumor agents. Inhibits osteoclastic bone resorption.

Product Specification

Alternative Name:	Mycotrienin II, T 23II

Formula:	C₃₆H₅₀N₂O₈

MW:	638.8

Purity:	≥95% (HPLC)

Appearance:	Yellow powder.

CAS:	82189-04-6

RTECS:	AY4553430

Source/Host:	Isolated from Streptomyces sp. MST-AS5998.

Solubility:	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.

Long Term Storage:	-20°C

Hazard:	TOXIC.

Handling:	Protect from light.

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Product Literature References

Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption: D. Feuerbach, et al.; J. Biol. Chem. 270, 25949 (1995), Abstract; Full Text

Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluorouracil by mycotrienins and mycotrienols: M. Kuwano, et al.; Gann. 74, 759 (1983), Abstract;

Studies on mycotrienin antibiotics, a novel class of ansamycins. I. Taxonomy, fermentation, isolation and properties of mycotrienins I and II: M. Sugita, et al.; J. Antibiot. (Tokyo) 35, 1460 (1982), Abstract;

Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II: M. Sugita, et al.; J. Antibiot. (Tokyo) 35, 1467 (1982), Abstract;

Mycotrienin, a new polyene antibiotic isolated from Streptomyces: C. Coronelli, et al.; J. Antibiot. (Tokyo) 20, 329 (1967), Abstract;