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Ansatrienin B

Antitumor antibiotic
 
ALX-380-204-M001 1 mg 408.00 USD
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Antitumor antibiotic, closely related to the cytotrienins. Displays potent anticancer activities. Significantly potentiates the action of several clinical antitumor agents. Inhibits osteoclastic bone resorption.

Product Specification

Alternative Name:Mycotrienin II, T 23II
 
Formula:C36H50N2O8
 
MW:638.8
 
Source:Isolated from Streptomyces sp. MST-AS5998.
 
CAS:82189-04-6
 
RTECS:AY4553430
 
Purity:≥95% (HPLC)
 
Appearance:Yellow powder.
 
Solubility:Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
380-204
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380-204

Product Literature References

Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption: D. Feuerbach, et al.; J. Biol. Chem. 270, 25949 (1995), Abstract; Full Text
Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluorouracil by mycotrienins and mycotrienols: M. Kuwano, et al.; Gann. 74, 759 (1983), Abstract;
Studies on mycotrienin antibiotics, a novel class of ansamycins. I. Taxonomy, fermentation, isolation and properties of mycotrienins I and II: M. Sugita, et al.; J. Antibiot. (Tokyo) 35, 1460 (1982), Abstract;
Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II: M. Sugita, et al.; J. Antibiot. (Tokyo) 35, 1467 (1982), Abstract;
Mycotrienin, a new polyene antibiotic isolated from Streptomyces: C. Coronelli, et al.; J. Antibiot. (Tokyo) 20, 329 (1967), Abstract;

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