Anguinomycin A

Antitumor antibiotic



ALX-380-202-MC01	0.1 mg	500.00 USD

Antitumor antibiotic. Displays nanomolar cytotoxicity to murine P388 leukemia cells. Analog of leptomycin B (Prod. No. ALX-380-100), an inhibitor of nuclear protein export.

Product Specification

Alternative Name:	5-Demethylleptomycin A, KR 2827A

Formula:	C₃₁H₄₄O₆

MW:	512.7

Purity:	≥95% (HPLC)

Appearance:	Clear film.

CAS:	111278-01-4

Source/Host:	Isolated from Streptomyces sp. MST-AS5546.

Solubility:	Soluble in 100% ethanol (recommended) or methanol. Unstable in DMSO.

Long Term Storage:	-20°C

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Product Literature References

Anguinomycins C and D, new antitumor antibiotics with selective cytotoxicity against transformed cells: Y. Hayakawa, et al.; J. Antibiot. (Tokyo) 48, 954 (1995), Abstract;

New antitumor antibiotics, anguinomycins A and B: Y. Hayakawa, et al.; J. Antibiot. (Tokyo) 40, 1349 (1987), Abstract;