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CJ-21058

SecA inhibitor
 
ALX-380-149-M001 1 mg 201.00 USD
 
ALX-380-149-M005 5 mg 869.00 USD
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Tetramic acid antibiotic. SecA inhibitor. Antibacterial, antifungal and cytotoxic agent. Methyl analog of equisetin.

Product Specification

Formula:C23H33NO4
 
MW:387.5
 
Source:Isolated from Phoma sp.
 
CAS:405072-57-3
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO, methanol or methylene chloride.
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:After reconstitution protect from light at -20°C.
 
380-149
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380-149

General Literature References

Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities: B. Patham, et al.; Biocheem. J. 419, 507 (2009), Abstract;
Discovery of the first SecA inhibitors using structure-based virtual screening: M. Li, et al.; BBRC 386, 839 (2008), Abstract;
CJ-21,058, a new SecA inhibitor isolated from a fungus: Y. Sugie, et al.; J. Antibiot. (Tokyo) 55, 25 (2002), Abstract;

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