Antibiotic with antibacterial, antifungal and antiprotozoal activity. Cytotoxic against several tumor cell lines in vitro.
Product Specification
| Alternative Name: | NSC350598, 3-Acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)furanone |
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| Identity: | Identity determined by 1H-NMR. |
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| Formula: | C10H14O5 |
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| MW: | 214.2 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white crystals. |
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| CAS: | 510-18-9 |
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| Source/Host: | Isolated from Streptomyces ramulosus. |
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| Solubility: | Soluble in methanol or DMSO. |
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| Long Term Storage: | -20°C |
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Product Literature References
The structure and absolute configuration of acetomycin: F.H. Cano, et al.; Acta Crystallogr. C.
44, 919 (1988),
Abstract;
Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo: S.W. Mamber, et al.; J. Antibiot. (Tokyo)
40, 73 (1987),
Abstract;
Biological effects of acetomycin. II. Inactivation by esterases in vitro: S.W. Mamber, et al.; J. Antibiot. (Tokyo)
40, 77 (1987),
Abstract;
The structure of acetomycin. Spectroscopic characterization and X-ray analysis of a bromo derivative: H. Uhr, et al.; J. Antibiot. (Tokyo)
38, 1684 (1985),
Abstract;