Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Becatecarin

Topoisomerase II inhibitor
 
ALX-380-119-M001 1 mg 1,272.00 USD
Do you need bulk/larger quantities?
 
Semisynthetic water-soluble derivative of rebeccamycin. Antitumor antibiotic. Topoisomerase II inhibitor. DNA intercalating agent.

Product Specification

Alternative Name:6-N-[2-(Diethylamino)ethyl]rebeccamycin, NSC 655649, BMY-27557-14, BMS-181176, XL 119
 
Formula:C33H34Cl2N4O7
 
MW:669.6
 
Source:Semisynthetic.
 
CAS:119673-08-4
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:Yellow solid.
 
Solubility:Soluble in water (pH-dependent) or DMSO.
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:After reconstitution protect from light at -20°C.
 
380-119
Please mouse over
380-119

Product Literature References

Becatecarin (Helsinn Healthcare): G.W. Rewcastle; IDrugs 8, 838 (2005), Abstract;
Phase I and pharmacokinetic study of sequences of the rebeccamycin analogue NSC 655649 and cisplatin in patients with advanced solid tumors: A.D. Ricart, et al.; Clin. Cancer Res. 11, 8728 (2005), Abstract; Full Text
Discovery of antitumor indolocarbazoles: rebeccamycin, NSC 655649, and fluoroindolocarbazoles: B.H. Long, et al.; Curr. Med. Chem. Anticancer Agents 2, 255 (2002), Abstract;
Water soluble derivatives of rebeccamycin: T. Kaneko, et al.; J. Antibiot. 43, 125 (1990), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Topoisomerase
By biological activity:
Topoisomerase Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,