Actinomycin X₂

Antitumor antibiotic



ALX-380-080-M001	1 mg	164.00 USD

Antitumor antibiotic. Has higher cytotoxicity toward cultured human leukemia (HL-60) cells than actinomycin D (Prod. No. ALX-380-009). Induces cell death via apoptosis.

Product Specification

Identity:	Determined by ¹H-NMR: Identical to standard reference.

Formula:	C₆₂H₈₄N₁₂O₁₇

MW:	1269.4

Purity:	≥95% (solvent free)

Appearance:	Orange crystals.

CAS:	18865-48-0

Source/Host:	Isolated from Streptomyces sp.

Solubility:	Soluble in methanol, acetone or chloroform.

Long Term Storage:	+4°C

Hazard:	TOXIC.

Handling:	Keep cool and dry.

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Product Literature References

Characterization of Streptomyces MITKK-103, a newly isolated actinomycin X2-producer: K. Kurosawa, et al.; Appl. Microbiol. Biotechnol. 72, 145 (2006), Abstract;

Correlation of actinomycin X2 to the lipid profile in static and shaken cultures of Streptomyces nasri strain YG62: M.Y. el-Naggar, et al.; Microbios. 100, 117 (1999), Abstract;

Nomenclature of the Actinomycins: S.A. Waksman, et al.; PNAS 44, 602 (1958), Abstract;