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Gallidermin

Antibiotic
 
ALX-380-072-M005 5 mg Inquire for pricing
 
ALX-380-072-M001 1 mg Inquire for pricing
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Antibiotic peptide/lantibiotic. Interferes with bacterial cell wall biosynthesis.

Product Specification

Alternative Name:6L-Epidermin
 
Formula:C98H141N25O23S4
 
MW:2165.7
 
Source:Isolated from Staphylococcus gallinarum Tü3928.
 
CAS:117978-77-5
 
Purity:≥90% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in water, 100% ethanol or methanol (1mg/ml).
 
Shipping:Ambient
 
Long Term Storage:+4°C
 

Product Literature References

Circumventing the effect of product toxicity: development of a novel two-stage production process for the lantibiotic gallidermin: G. Valsesia, et al.; Appl. Environ. Microbiol. 73, 1635 (2007), Abstract; Full Text
Dual role of GdmH in producer immunity and secretion of the Staphylococcal lantibiotics gallidermin and epidermin: M. Hille, et al.; Appl. Environ. Microbiol. 67, 1380 (2001), Abstract; Full Text
Identification of unusual amino acids in peptides using automated sequential Edman degradation coupled to direct detection by electrospray-ionization mass spectrometry: T.B. Walk, et al.; Biopolymers 49, 329 (1999), Abstract;
Secretion of the lantibiotics epidermin and gallidermin: sequence analysis of the genes gdmT and gdmH, their influence on epidermin production and their regulation by EpiQ: A. Peschel, et al.; Mol. Gen. Genet. 254, 312 (1997), Abstract;
Isolation and characterization of genetically engineered gallidermin and epidermin analogs: B. Ottenwalder, et al.; Appl. Environ. Microbiol. 61, 3894 (1995), Abstract; Full Text
Gallidermin: a new lanthionine-containing polypeptide antibiotic: R. Kellner, et al.; Eur. J. Biochem. 177, 53 (1988), Abstract;

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