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Cytochalasin C

Antibiotic
 
ALX-380-069-M001 1 mg 79.00 USD
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Antibiotic. Disrupts the actin microfilament cytoskeleton and inhibits the cytoplasmic dividing of a cell. Has been found to be ten times less toxic in mice than cytochalasin D (Prod. No. BML-T109) but with essentially the same biological effectiveness against cells in culture.

Product Specification

Formula:C30H37NO6
 
MW:507.6
 
Source:Isolated from Metarhizium anisopliae.
 
CAS:22144-76-9
 
MI:14: 2790
 
RTECS:HA5300500
 
Purity:≥98% (TLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO, 100% ethanol or dichloromethane.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-380-069
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ALX-380-069

Product Literature References

Alteration in cell morphology triggers transforming growth factor-beta 1, collagenase, and tissue inhibitor of metalloproteinases-I expression in normal and hypertrophic scar fibroblasts: M. Varedi, et al.; J. Invest. Dermatol. 104, 118 (1995), Abstract;
Actin assembly activity of cytochalasins and cytochalasin analogs assayed using fluorescence photobleaching recovery: E.A. Walling, et al.; Arch. Biochem. Biophys. 264, 321 (1988), Abstract;

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