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Cytochalasin A

HIV-1 protease inhibitor
 
ALX-380-057-M001 1 mg 62.00 USD
 
ALX-380-057-M005 5 mg 211.00 USD
 
ALX-380-057-M010 10 mg 344.00 USD
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Antibiotic. Fungal toxin. Inhibits glucose transport, actin polymerisation and blocks the formation of microtubuli. Inhibits cell division. Inhibits HIV-1 protease.

Product Specification

Formula:C29H35NO5
 
MW:477.6
 
Source:Isolated from Drechslera dematoidea.
 
CAS:14110-64-6
 
MI:14: 2790
 
Purity:≥98% (HPLC, TLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in acetone, DMSO or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-380-057
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ALX-380-057

Product Literature References

Effect of cytochalasin A on apical growth, actin cytoskeleton organization and enzyme secretion in Aspergillus nidulans: S. Torralba, et al.; Microbiology 144 (Pt 1), 45 (1998), Abstract;
L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. III. Biological activity: R.B. Lingham, et al.; J. Antibiot. 45, 686 (1992), Abstract;
Cytochalasin A inhibits B-lymphocyte capping and activation by antigens: G. Teti, et al.; Immunol. Lett. 3, 151 (1981), Abstract;
The action of cytochalasin A on the in vitro polymerization of brain tubulin and muscle G-actin: R.H. Himes & L.L. Houston; J. Supramol. Struct. 5, 81 (1976), Abstract;

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