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Verruculogen

Cell cycle inhibitor
 
ALX-380-056-M001 1 mg 120.00 USD
 
ALX-380-056-M005 5 mg 388.00 USD
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Neurotoxin that acts as an inhibitor of the M phase of the mammalian cell cycle. Inhibits Ca2+-activated K+ channels. Decreases GABA levels in CNS.

Product Specification

Formula:C27H33N3O7
 
MW:511.6
 
Source:Isolated from Penicillium verruculosum.
 
CAS:12771-72-1
 
RTECS:JH4920000
 
Purity:≥95% (HPLC, TLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in ethyl acetate, DMSO, 100% ethanol or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
ALX-380-056
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ALX-380-056

Product Literature References

Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.: I. Kosalec, et al.; Acta Pharm. 55, 357 (2005), Abstract;
Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico- chemical properties and structures: C.B. Cui, et al.; J. Antibiot. (Tokyo) 49, 534 (1996), Abstract;
Tremorgenic indole alkaloids potently inhibit smooth muscle high- conductance calcium-activated potassium channels: H.H. Knaus, et al.; Biochemistry 33, 5819 (1994), Abstract;

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