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Fusidic acid . sodium salt

Elongation factor G inhibitor
 
ALX-380-011-M050 50 mg 35.00 USD
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Antibiotic which suppresses nitric oxide (NO) toxicity in pancreatic islet cells. Inhibits protein synthesis by inhibition of elongation factor G at the level of the ribosome.

Product Specification

Formula:C31H47O6 . Na
 
MW:515.7 . 23.0
 
CAS:751-94-0
 
MI:14: 4317
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
ALX-380-011
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ALX-380-011

Product Literature References

Dumb and dumber--the potential waste of a useful antistaphylococcal agent: emerging fusidic acid resistance in Staphylococcus aureus: B.P. Howden & M.L. Grayson; Clin. Infect. Dis. 42, 394 (2006), Review, Abstract;
Fusidic acid in vitro activity: P. Collignon and J. Turnidge; Int. J. Antimicrob. Agents 12, S45 (1999), Review, Abstract;
Fusidic acid non-antibacterial activity: K. Christiansen; Int J Antimicrob Agents 12, S73 (1999), Review, Abstract;
Fusidic acid suppresses nitric oxide toxicity in pancreatic islet cells: V. Burkart, et al.; Biochem. Pharmacol. 48, 1379 (1994), Abstract;
Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics: N. Tanaka, et al.; BBRC 30, 278 (1968), Abstract;
On the Mode of Action of Fusidic Acid: C.L. Harvey, et al.; Biochemistry 5, 3320 (1966), Abstract;
Fusidic acid: a new antibiotic: W.O. Godtfredsen, et al.; Nature 193, 987 (1962), Abstract;

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