Cyclopenol



ALX-350-420-M001	1 mg	134.00 USD

ALX-350-420-M005	5 mg	536.00 USD

Cyclopenol is a benzodiazepine metabolite produced in several species of Penicillium. It displays antimicrobial and phytotoxic properties. Intermediate in the biosynthesis of viridicatins, strong inhibitors of the tumor necrosis factor alpha (TNFα)- induced replication of human HIV.

Product Specification

Alternative Name:	3’-(3-Hydroxyphenyl)-4-methylspiro(3H-1,4-benzodiazepine-3,2’-oxirane)-2,5(1H,4H)-dione

Formula:	_{C₁₇H₁₄N₂O₄}

MW:	310.3

Purity:	≥99% (HPLC)

Appearance:	Off-white solid.

CAS:	20007-85-6

Source/Host:	Isolated from Penicillium sp.

Long Term Storage:	-20°C

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Product Literature References

Isolation and characterization of the fungal metabolite 3-O-methylviridicatin as an inhibitor of tumour necrosis factor alpha-induced human immunodeficiency virus replication: A. Heguy, et al.; Antivir. Chem. Chemother. 9, 149 (1998), Abstract;

The Biological Properties of Cyclopenin and Cyclopenol: H.G. Cutler, et al.; Plant and Cell Physiol. 25, 257 (1984),

On the biosynthesis of cyclopenin and cyclopenol, benzodiazepine alkaloids from Penicillium cyclopium Westling: L. Nover & M. Luckner; Eur. J. Biochem. 10, 268 (1969), Abstract;