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Okadaic acid C8-diol ester

 
ALX-350-392-C100 100 µg 714.00 USD
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Fragment of a precursor to okadaic acid. Inactive against protein phosphatases in vitro. Potent toxin to whole cells, suggesting transport across the cell membrane and cleavage of the ester bond by cellular esterases.

Product Specification

Formula:C52H80O14
 
MW:929.2
 
Source:Isolated from Prorocentrum lima.
 
CAS:318536-96-8
 
Purity:≥90%
 
Appearance:Colorless solid.
 
Solubility:Soluble in methanol or DMSO.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
350-392
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350-392

Product Literature References

Isolation and identification of a cis-C8-diol-ester of okadaic acid from Dinophysis acuta in New Zealand: C.O. Miles, et al.; Toxicon 48, 195 (2006), Abstract;
Discovery of okadaic acid esters in the toxic dinoflagellate Dinophysis acuta from New Zealand using liquid chromatography/tandem mass spectrometry: T. Suzuki, et al.; Rapid Commun. Mass Spectrom. 18, 1131 (2004), Abstract;
Comparative toxicity of the diarrhetic shellfish poisons, okadaic acid, okadaic acid diol-ester and dinophysistoxin-4, to the diatom Thalassiosira weissflogii: A.J. Windust, et al.; Toxicon 35, 1591 (1997), Abstract;
Biosynthesis of DTX-4: Confirmation of a Polyketide Pathway, Proof of a Baeyer−Villiger Oxidation Step, and Evidence for an Unusual Carbon Deletion Process: J.L.C. Wright, et al.; JACS 118, 8757 (1996), Abstract;
New diol esters isolated from cultures of the dinoflagellates Prorocentrum lima and Prorocentrum concavum: T. Hu, et al.; J. Nat. Prod. 55, 1631 (1992), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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