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Aerothionin

Antimycobacterial agent
 
ALX-350-389-M001 1 mg 138.00 USD
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Bromotyrosine derivative with antimycobacterial activity.

Product Specification

Formula:C24H26Br4N4O8
 
MW:818.1
 
Source:Isolated from sponge Aplysina cavernicola.
 
CAS:28714-26-3
 
Purity:≥96% (HPLC)
 
Identity:Determined by 1H-NMR and ESI-MS.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
350-389
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350-389

Product Literature References

Bioactive constituents from the marine crinoid Himerometra magnipinna: N. Shao, et al.; J. Nat. Prod. 70, 869 (2007), Abstract;
Asymmetric synthesis of aerothionin, a marine dimeric spiroisoxazoline natural product, employing optically active spiroisoxazoline derivative: T. Ogamino, et al.; THL 47, 727 (2006),
Aerothionin, a bromotyrosine derivative with antimycobacterial activity from the marine sponge Aplysina gerardogreeni (Demospongia): R. Encarnacion-Dimayuga, et al.; Pharm. Biol. 41, 384 (2003), Abstract;
Syntheses of the Marine Metabolites Verongamine, Hemibastadin-2, and Aerothionin Using the Cyano Ylide Coupling Methodology: H.H. Wasserman & J. Wang; J. Org. Chem. 63, 5581 (1998), Abstract;
Exudation of biologically-active metabolites in the sponge Aplysina fistularis: R.P. Walker, et al.; Mar. Biol. 88, 27 (1985), Abstract;
Total Syntheses of (±)-Aerothionin, (±)-Homoaerothionin, and (±)-Aerophobin-1: S. Nishiyama & S. Yamamura; Bull. Chem. Soc. Jpn. 58, 3453 (1985), Abstract; Full Text
Aerothionin and homoaerothionin: two tetrabromo spirocyclohexadienylisoxazoles from Verongia sponges: K. Moody, et al.; J. Chem. Soc., Perkin Trans. 1 18 (1972), Abstract;

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