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Hassallidin B

Broad spectrum antifungal compound
 
ALX-350-380-C050 50 µg 150.00 USD
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Broad spectrum antifungal compound. Active against Candida, Acremonium, Cryptococcus neoformans, Trichosporon, Aspergillus, Fusarium sambucium (minimal inhibition concentration (MIC) range: 4-16μg/ml). Moderate activity against cancerous cells (Jurkat ATCC-TIB-152, L 929). No activity against bacteria (Bacillus subtilis, Streptomyces versicolor, Escherichia coli).

Product Specification

Formula:C68H109N11O28
 
MW:1527.7
 
Source:Isolated from Hassallia sp.
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol, methanol or DMSO; insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Hygroscopic.
 
350-380
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350-380

Product Literature References

Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway: J. Vestola, et al.; PNAS 6, 111 (2014), Abstract; Full Text
Genome-derived insights into the biology of the hepatotoxic bloom-forming cyanobacterium Anabaena sp. strain 90: H.Wang, et al.; BMC Genomics 13, 613 (2012), Abstract; Full Text
Identification and toxigenic potential of a Nostoc sp.: B. Nowruzi, et al.; Algae 27, 303 (2012), Full Text
Hassallidin B--second antifungal member of the Hassallidin family: T. Neuhof, et al.; Bioorg. Med. Chem. Lett. 16, 4220 (2006), Abstract;

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Isolated from Hassallia sp., ≥98% (HPLC) | Print as PDF
 
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