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Loganin

Immunomodulator
 
ALX-350-363-M025 25 mg 114.00 USD
 
ALX-350-363-M100 100 mg 324.00 USD
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Iridoid glycoside associated with immunostimmulatory and hepatoprotective activity. Key starting material for the biosynthesis of indolalkaloids. Substrate for cytochrome P450.

Product Specification

Formula:C17H26O10
 
MW:390.4
 
Source:Isolated from Cornus officinalis.
 
CAS:18524-94-2
 
MI:14: 5560
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water; less soluble in 96% ethanol; sparingly soluble in 100% ethanol; insoluble in ether, petroleum ether, ethyl acetate or acetone.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
350-363
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350-363

Product Literature References

Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase: S. Irmler, et al.; Plant J. 24, 797 (2000), Abstract;
Prevention of galactosamine - induced hepatic damage by the natural product loganin from the plant strychnos nux-vomica: studies on isolated hepatocytes and bile flow in rat: P.K.S. Visen, et al.; Phytother. Res. 12, 405 (1998),
Studies on the profile of immunostimulant activities of modified iridoid glycosides: V.T. Mathad, et al.; Bioorg. Med. Chem. 6, 605 (1998), Abstract;
Alkaloid biosynthesis. 13. The structure, stereochemistry, and biosynthesis of loganin: A.R. Battersby, et al.; J. Chem. Soc. 5, 721 (1969), Abstract;
Biosynthesis of methylcyclopentane monoterpenoids. IV. Verbenalin: A.G. Horodysky, et al.; J. Biol. Chem. 244, 3110 (1969), Abstract; Full Text

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