Potent neurotoxin produced by a diverse range of fungi, most notably Penicillium species. Inhibits growth of Gram-positive bacteria. Inhibits cytochrome p450.
Product Details
| Formula: | C22H23N5O2 |
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| MW: | 389.5 |
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| Source: | Isolated from MST-FP1764. |
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| CAS: | 58735-64-1 |
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| RTECS: | UQ4730500 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Toxigenic potentiality of Aspergillus flavus and Aspergillus parasiticus strains isolated from black pepper assessed by an LC-MS/MS based multi-mycotoxin method: P. Yogendrarajah; Food Microbiol.
52, 185 (2015),
Application(s): Cell culture ,
Abstract;
The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes: M. Keblys, et al.; Mycopathologia
158, 317 (2004),
Abstract;
Inhibitory effects of roquefortine on hepatic cytochromes P450: C. Aninat and M. Delaforge; Adv. Exp. Med. Biol.
500, 331 (2001),
Abstract;
Molecular requirements for inhibition of cytochrome p450 activities by roquefortine: C. Aninat, et al.; Chem. Res. Toxicol.
14, 1259 (2001),
Abstract;
Antimicrobial action of roquefortine: B. Kopp-Holtwiesche and H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol.
10, 41 (1990),
Abstract;
Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti: S. Ohmomo, et al.; Agric. Biol. Chem. 39, 1333 (1975),
