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Roquefortine C

Cytochrome P450 inhibitor
 
ALX-350-342-MC05 0.5 mg 407.00 USD
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Potent neurotoxin produced by a diverse range of fungi, most notably Penicillium species. Inhibits growth of Gram-positive bacteria. Inhibits cytochrome p450.

Product Specification

Formula:C22H23N5O2
 
MW:389.5
 
Source:Isolated from MST-FP1764.
 
CAS:58735-64-1
 
RTECS:UQ4730500
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
350-342
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350-342

Product Literature References

Toxigenic potentiality of Aspergillus flavus and Aspergillus parasiticus strains isolated from black pepper assessed by an LC-MS/MS based multi-mycotoxin method: P. Yogendrarajah; Food Microbiol. 52, 185 (2015), Application(s): Cell culture , Abstract;
The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes: M. Keblys, et al.; Mycopathologia 158, 317 (2004), Abstract;
Inhibitory effects of roquefortine on hepatic cytochromes P450: C. Aninat and M. Delaforge; Adv. Exp. Med. Biol. 500, 331 (2001), Abstract;
Molecular requirements for inhibition of cytochrome p450 activities by roquefortine: C. Aninat, et al.; Chem. Res. Toxicol. 14, 1259 (2001), Abstract;
Antimicrobial action of roquefortine: B. Kopp-Holtwiesche and H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol. 10, 41 (1990), Abstract;
Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti: S. Ohmomo, et al.; Agric. Biol. Chem. 39, 1333 (1975),

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