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Psoralidin

PTP1B inhibitor
 
ALX-350-323-M001 1 mg 180.00 USD
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Antineoplastic compound. Cytotoxic against stomach cancer cell lines. Shows antibacterial activity against Shigella sonnei and S. flexneri. Shows strong antioxidant activity and inhibits tyrosine phosphatase 1B (PTP1B) activity. Was shown to possess potent antidepressant properties.

Product Specification

Formula:C20H16O5
 
MW:336.3
 
Source:Isolated from Psoralea corylifolia.
 
CAS:18642-23-4
 
Purity:≥97% (HPLC)
 
Identity:Determined by 1H-NMR, 13C-NMR and MS.
 
Appearance:Yellow oily solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
350-323
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350-323

Product Literature References

Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice: L.T. Yi, et al.; Prog. Neuropsychopharmacol. Biol. Psychiatry 32, 510 (2008), Abstract;
Antioxidants from a Chinese medicinal herb - Psoralea corylifolia L.: G. Jiangning, et al.; Food Chem. 91, 287 (2005),
In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia: Y.C. Kim, et al.; Planta Med. 71, 87 (2005), Abstract;
Antibacterial compounds from the seeds of Psoralea corylifolia: N.A. Khatune, et al.; Fitoterapia 75, 228 (2004), Abstract;
Inducible flavone in oats (Avena sativa) is a novel defense against plant-parasitic nematodes: I.R. Soriano, et al.; Phytopathology 94, 1207 (2004), Abstract; Full Text
Cytotoxic constituents of Psoralea corylifolia: W. Mar, et al.; Arch. Pharm. Res. 24, 211 (2001), Abstract;
Coumarins: A. Estevez-Braun & A.G. Gonzalez; Nat. Prod. Rep. 14, 465 (1997), Abstract;
The cytotoxicity of psoralidin from Psoralea corylifolia: Y.M. Yang, et al.; Planta Med. 62, 353 (1996), Abstract;
Influence of nitrogen on accumulation of isosojagol (a newly detected coumestan in soybean) and associated isoflavonoids in roots and nodules of mycorrhizal and non-mycorrhizal soybean: D. Morandi & J.L. Le Quere; New Phytol. 117, 75 (1991), Full Text

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