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Pseurotin A

Chitin synthase inhibitor
 
ALX-350-300-M001 1 mg 217.00 USD
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Antibiotic. Inhibitor of chitin synthase. Cytotoxic. Has nematicidal activity.

Product Specification

Formula:C22H25NO8
 
MW:431.5
 
Source:Isolated from Aspergillus fumigatus.
 
CAS:58523-30-1
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:White to off-white powder.
 
Solubility:Soluble in methanol or ethyl acetate; poorly soluble in water.
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:After reconstitution protect from light at -20°C.
 
350-300
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350-300

Product Literature References

Fumiquinones A and B, nematicidal quinones produced by Aspergillus fumigatus: A. Hayashi, et al.; Biosci. Biotechnol. Biochem. 71, 1697 (2007), Abstract;
Identification of a hybrid PKS/NRPS required for pseurotin A biosynthesis in the human pathogen Aspergillus fumigatus: S. Maiya, et al.; Chembiochem 8, 1736 (2007), Abstract;
Directed biosynthesis of fluorinated pseurotin A, synerazol and gliotoxin: Y. Igarashi, et al.; J. Antibiot. 57, 748 (2004), Abstract;
Novel neuritogenic activities of pseurotin A and penicillic acid: D. Komagata, et al.; J. Antibiot. 49, 958 (1996), Abstract;

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