3-ATA

CDK4 inhibitor



ALX-350-273-M001	1 mg	62.00 USD

ALX-350-273-M005	5 mg	248.00 USD

Specific CDK4 inhibitor (IC₅₀=3.1µM) inducing growth inhibition of p16-altered tumors.

Product Specification

Alternative Name:	3-Amino-9-thio(10H)-acridone

Formula:	C₁₃H₁₀N₂S

MW:	226.3

Purity:	≥95%

Appearance:	White to off-white solid powder.

CAS:	12982-10-85

Solubility:	Soluble in DMSO or dimethyl formamide.

Long Term Storage:	+20°C

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Product Literature References

3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons: E. Verdaguer, et al.; Neuroscience 120, 599 (2003), Abstract;

The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4: A. Kubo, et al.; Clin. Cancer Res. 5, 4279 (1999), Abstract;