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3-ATA

CDK4 inhibitor
 
ALX-350-273-M005 5 mg 289.00 USD
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Specific CDK4 inhibitor (IC50=3.1µM) inducing growth inhibition of p16-altered tumors.

Product Specification

Alternative Name:3-Amino-9-thio(10H)-acridone
 
Formula:C13H10N2S
 
MW:226.3
 
CAS:12982-10-85
 
Purity:≥95%
 
Appearance:White to off-white solid powder.
 
Solubility:Soluble in DMSO or dimethyl formamide.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
ALX-350-273
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ALX-350-273

Product Literature References

Elevated Serum Antibody Levels against Cyclin L2 in Patients with Esophageal Squamous Cell Carcinomai : H. Shimada, et al.; J. Cancer Sci. Ther. 7, 60 (2015), Application(s): Cell Culture, Full Text
3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons: E. Verdaguer, et al.; Neuroscience 120, 599 (2003), Abstract;
The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4: A. Kubo, et al.; Clin. Cancer Res. 5, 4279 (1999), Abstract;

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