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Phalloidin

Actin ligand
 
ALX-350-265-M001 1 mg 182.00 USD
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Replaces Prod. #: BML-T111

Binds to polymeric actin with high affinity. Stabilizes filaments and decreases concentration of monomeric actin.

Product Specification

Formula:C35H48N8O11S
 
MW:788.9
 
Source:Isolated from Amanita phalloides mushrooms.
 
CAS:17466-45-4
 
MI:14: 7196
 
Purity:≥90%
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO, dimethyl formamide, methanol, 100% ethanol (10mg/ml) or water (1mg/ml, warm).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
350-265
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350-265

Product Literature References

Position and orientation of phalloidin in F-actin determined by X-ray fiber diffraction analysis: T. Oda, et al.; Biophys. J. 88, 2727 (2005), Abstract;
Effects of cytochalasin and phalloidin on actin: J.A. Cooper; J. Cell. Biol. 105, 1473 (1987), (Review), Abstract;
What we have learned from phalloidin: M. Frimmer; Toxicol Lett. 35, 169 (1987), Abstract;
Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth: J. Wehland, et al.; PNAS 74, 5613 (1977), Abstract;
Interaction of actin with phalloidin: polymerization and stabilization of F-actin: P. Dancker, et al.; Biochim. Biophys. Acta 400, 407 (1975), Abstract;
Interaction of phalloidin with actin: A.M. Lengsfeld, et al.; PNAS 71, 2803 (1974), Abstract;

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