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Genistin

TdT inhibitor
 
ALX-350-247-M010 10 mg 137.00 USD
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Glucoside of genistein (Prod. No. ALX-350-006) found in soy beans. Useful as a negative control for genistein and other tyrosine kinase inhibitors. Selective inhibitor of terminal deoxyribonucleotidyltransferase (TdT). Displays antioxidant and anticarcinogenic properties.

Product Specification

Alternative Name:Genistein-7-O-glucoside
 
Formula:C21H20O10
 
MW:432.4
 
CAS:529-59-9
 
MI:14: 4391
 
RTECS:DJ3093000
 
Purity:≥98% (HPLC, TLC)
 
Appearance:Off-white to light yellow powder.
 
Solubility:Soluble in DMSO or dilute aqueous base; insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
ALX-350-247
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ALX-350-247

Product Literature References

Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells: E.J. Choi, et al.; Life Sci. 80, 1403 (2007), Abstract;
Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells: A. Russo, et al.; J. Nutr. Biochem. 17, 103 (2006), Abstract;
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin: Y. Uchiyama, et al.; Biochim. Biophys. Acta 1725, 298 (2005), Abstract;
Daidzein and genistein but not their glucosides are absorbed from the rat stomach: M.K. Piskula, et al.; FEBS Lett. 447, 287 (1999), Abstract;
Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones: H.G. Shertzer, et al.; Chem. Biol. Interact. 123, 31 (1999), Abstract;
Soybean isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis: S. Ji, et al.; J. Nutr. 129, 1291 (1999), Abstract;

Related Products

Genistein (synthetic) 

Tyrosine kinase inhibitor
446-72-0, Synthetic., ≥98% (HPLC) | Print as PDF
 
ALX-350-006-M010 10 mg 34.00 USD
 
ALX-350-006-M025 25 mg 59.00 USD
 
ALX-350-006-M050 50 mg 109.00 USD
 
ALX-350-006-M100 100 mg 175.00 USD
 
ALX-350-006-G001 1 g 578.00 USD
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