Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

R,S-Sulforaphane

Carcinogenesis inhibitor
 
ALX-350-232-M025 25 mg 170.00 USD
Do you need bulk/larger quantities?
 
R,S-Sulforaphane is a synthetic version of the naturally occurring compound, R-sulforaphane, from Broccoli. It is a racemic mixture of both the R and S isomers.
Potent, selective inducer of phase II detoxification enzymes. Inhibits chemically induced mammary tumor formation in rats. Inhibits LPS-induced HMGB1 (high mobility group box 1) secretion.

Product Specification

Alternative Name:D,L-Sulforaphane, 1-Isothiocyanato-4-methylsulfinyl-butane
 
Formula:C6H11NOS2
 
MW:177.3
 
Source:Synthetic.
 
CAS:4478-93-7 (unspecified stereo)
 
MI:14: 8962
 
Purity:≥98% (UPLC)
 
Identity:Identity determined by 1H-NMR and MS.
 
Appearance:Slightly yellowish liquid.
 
Solubility:Soluble in methanol or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
350-232
Please mouse over
350-232

Product Literature References

Simultaneous quantification of sulforaphene and sulforaphane by reverse phase HPLC and their content in Raphanus sativus L. var. caudatus Alef extracts: S. Sangthong, et al.; Food. Chem. 201, 139 (2016), Application(s): Standard, Abstract;
4-Methylthiobutyl isothiocyanate (Erucin) from rocket plant dichotomously affects the activity of human immunocompetent cells: C. Gründemann, et al.; Phytomedicine 22, 369 (2015), Application(s): Gas Chromatography - Mass Spectrometry , Abstract;
Synergy between sulforaphane and selenium in protection against oxidative damage in colonic CCD841 cells: Y. Wang, et al.; Nutr. Res. 35, 610 (2015), Abstract;
Protective effect of sulforaphane against oxidative stress: Recent advances: C.E. Guerrero-Beltran, et al.; Exp. Toxicol. Pathol. 64, 503 (2012), Abstract;
Sulforaphane targets pancreatic tumor-initiating cells by NF-{kappa}B-induced anti-apoptotic signaling: G. Kallifatidis, et al.; Gut 58, 949 (2009), Abstract;
The phase 2 enzyme inducers ethacrynic acid, DL-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells: M.E. Killeen, et al.; J. Pharmacol. Exp. Ther. 316, 1070 (2006), Abstract;
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase: M.C. Myzak, et al.; Cancer Res. 64, 5767 (2004), Abstract; Full Text
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates: Y. Zhang, et al.; PNAS 91, 3147 (1994), Abstract; Full Text
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure: Y. Zhang, et al.; PNAS 89, 2399 (1992), Abstract; Full Text

Related Literature

Product Flyers
Detect Activity of Major ABC Transporter Proteins
Detect Activity of Major ABC Transporter Proteins
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,