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Sedanolide

GST activator
 
ALX-350-229-M100 100 mg 155.00 USD
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Inducer of glutathione S-transferases and inhibitor of chemically induced carcinogenesis. Mosquitocidal, nematicidal and antifungal. Was shown to inhibit cyclooxygenase-1 and -2 (COX-1 and COX-2) as well as topoisomerase I and topoisomerase II.

Product Specification

Alternative Name:3-Butyl-3a,4,5,6-tetrahydro-1(3H)-isobenzofuranone
 
Formula:C12H18O2
 
MW:194.1
 
Source:Isolated from Apium graveolens L.
 
CAS:6415-59-4
 
Purity:≥98% (UHPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol or ethyl acetate.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
ALX-350-229
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ALX-350-229

Product Literature References

Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds: R.A. Momin & M.G. Nair; Phytomedicine 9, 312 (2002), Abstract;
Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds: R.A. Momin & M.G. Nair; J. Agric. Food Chem. 49, 142 (2001), Abstract;
Sedanolide, a natural phthalide from celery seed oil: effect on hydrogen peroxide and tert-butyl hydroperoxide-induced toxicity in HepG2 and CaCo-2 human cell lines: J.A. Woods, et al.; In Vitr. Mol. Toxicol. 14, 233 (2001), Abstract;
Chemoprevention of benzo[a]pyrene-induced forestomach cancer in mice by natural phthalides from celery seed oil: G.-Q. Zheng, et al.; Nutr. Cancer 19, 77 (1993), Abstract;

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