Caffeic acid methyl ester

Ornithine decarboxylase inhibitor



ALX-350-226-M050	50 mg	46.00 USD

Inhibitor of ornithine decarboxylase and protein tyrosine kinases. Has a strong inhibitory effect on human platelet aggregation. Shows antioxidant, antiproliferative and cytotoxic properties.

Product Specification

Alternative Name:	Methyl caffeate

Identity:	Identity determined by NMR and MS.

Formula:	C₁₀H₁₀O₄

MW:	194.2

Purity:	≥98% (HPLC)

Appearance:	Slightly yellowish solid.

CAS:	3843-74-1

Source/Host:	Synthetic.

Solubility:	Soluble in DMSO, methanol or acetone.

Long Term Storage:	-20°C

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Product Literature References

Phenolic acid derivatives with potential anticancer properties--a structure-activity relationship study. Part 1: methyl, propyl and octyl esters of caffeic and gallic acids: S.M. Fiuza, et al.; Bioorg. Med. Chem. 12, 3581 (2004), Abstract;

Anti-platelet effect of the constituents isolated from the barks and fruits of Magnolia obovata: M.K. Pyo, et al.; Arch. Pharm. Res. 25, 325 (2002), Abstract;

Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles: J.E. Burdette, et al.; J. Agric. Food Chem. 50, 7022 (2002), Abstract;

Phenolic compounds from Duchesnea chrysantha and their cytotoxic activities in human cancer cell: I.R. Lee & M.Y. Yang; Arch. Pharm. Res. 17, 476 (1994), Abstract;

Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth: C.V. Rao, et al.; Chem. Biol. Interactions 84, 277 (1992), Abstract;

Inhibition of platelet activation and endothelial cell injury by polyphenolic compounds isolated from Lonicera japonica Thunb: W.C. Chang & F.L. Hsu; Prostaglandins Leukot. Essent. Fatty Acids 45, 307 (1992), Abstract;