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Limonin

Carcinogenesis inhibitor
 
ALX-350-225-M050 50 mg 69.00 USD
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Bitter principle of citrus fruits. Inhibits chemically induced carcinogenesis. Inhibits HIV-1 replication. Shows antinociceptive effect. Does not possess any inherent antioxidant activity.

Product Specification

Alternative Name:Limonoic acid di-δ-lactone
 
Formula:C26H30O8
 
MW:470.5
 
Source:Isolated from grapefruit seed.
 
CAS:1180-71-8
 
MI:14: 5494
 
Purity:≥98% (UHPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol or glacial acetic acid; slightly soluble in water.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
ALX-350-225
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ALX-350-225

Product Literature References

Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside: A.P. Breksa, 3rd & G.D. Manners; J. Agric. Food Chem. 54, 3827 (2006), Abstract;
Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells: L. Battinelli, et al.; Planta Med. 69, 910 (2003), Abstract;
Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats: T. Tanaka, et al.; Biofactors 13, 213 (2000), Abstract;
Antinociceptive and anti-inflammatory activities of limonin isolated from the fruits of Evodia rutaecarpa var. bodinieri: H. Matsuda, et al.; Planta Med. 64, 339 (1998), Abstract;
Inhibition of Chemically Induced Carcinogenesis by Citrus Limonoids: L.K.T. Lam, et al.; ACS Symposium Series 546, 209 (1994), Abstract;
The effect of citrus limonoids on hamster buccal pouch carcinogenesis: E.G. Miller, et al.; Carcinogenesis 10, 1535 (1989), Abstract;
Antifeedant effects of nomilin on Spodoptera frugiperda and Trichoplusia ni under laboratory conditions: M.A. Altieri, et al.; Protect. Ecol. 6, 91 (1984),
Citrus limonoid by-products as insect control agents: J.A. Klocke & I. Kubo; Ent. Exp. & Appl. 32, 299 (1982), Abstract;
Nomilin, a new bitter component in grapefruit juice: R.L. Rouseff; J. Agric. Food Chem. 30, 504 (1982), Abstract;
Limonin and limonoids: chemistry, biochemistry, and juice bitterness: V.P. Maier, et al.; ACS Symposium Series 143, 63 (1980), Abstract;

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