Limonin

Carciogenesis inhibitor



ALX-350-225-M050	50 mg	62.00 USD

Bitter principle of citrus fruits. Inhibits chemically induced carcinogenesis. Inhibits HIV-1 replication. Shows antinociceptive effect. Does not possess any inherent antioxidant activity.

Product Specification

Alternative Name:	Limonoic acid di-δ-lactone

Formula:	C₂₆H₃₀O₈

MW:	470.5

Purity:	≥98% (HPLC)

Appearance:	White to off-white solid.

CAS:	1180-71-8

MI:	14: 5494

Source/Host:	Isolated from grapefruit seed.

Solubility:	Soluble in 100% ethanol or glacial acetic acid; slightly soluble in water.

Long Term Storage:	+20°C

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Product Literature References

Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside: A.P. Breksa, 3rd & G.D. Manners; J. Agric. Food Chem. 54, 3827 (2006), Abstract;

Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells: L. Battinelli, et al.; Planta Med. 69, 910 (2003), Abstract;

Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats: T. Tanaka, et al.; Biofactors 13, 213 (2000), Abstract;

Antinociceptive and anti-inflammatory activities of limonin isolated from the fruits of Evodia rutaecarpa var. bodinieri: H. Matsuda, et al.; Planta Med. 64, 339 (1998), Abstract;

L.K.T. Lam, et al.; ACS Symposium Series 546, 209 (1994),

The effect of citrus limonoids on hamster buccal pouch carcinogenesis: E.G. Miller, et al.; Carcinogenesis 10, 1535 (1989), Abstract;

M.A. Altieri, et al.; Protect. Ecol. 6, 91 (1984),

R.L. Rouseff; J. Agric. Food Chem. 30, 504 (1982),

J.A. Klocke & I. Kubo; Ent. Exp. & Appl. 32, 299 (1982),

V.P. Maier, et al.; ACS Symposium Series 143, 63 (1980),