C-glycosylated chromone compound. Competitive inhibitor of tyrosinase. Shows weak free radical scavenging activity. Anti-inflammatory. Modulates melanogenesis (pigmentation-altering agent). Used in the cosmetic industry.
Product Details
| Alternative Name: | Aloeresin B, NSC 631262, 8-β-D-Glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one |
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| Formula: | C19H22O9 |
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| MW: | 394.4 |
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| Source: | Isolated from Aloe sp. |
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| CAS: | 30861-27-9 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Identity determined by 1H-NMR and MS. |
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| Appearance: | Pale yellow to brown powder. |
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| Solubility: | Soluble in DMSO or 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Determination of aloesin and aloeresin A for the detection of aloe in beverages: M. Dell Agli, et al.; J. Agric. Food Chem.
55, 3363 (2007),
Abstract;
Aloeresin I, an anti-inflammatory 5-methylchromone from cape aloe: G. Speranza, et al.; Planta Med.
71, 79 (2005),
Abstract;
Aloesin inhibits hyperpigmentation induced by UV radiation: S. Choi, et al.; Clin. Exp. Dermatol.
27, 513 (2002),
Abstract;
Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in Aloe vera: A. Yagi, et al.; Planta Med.
68, 957 (2002),
Abstract;
Modulation of melanogenesis by aloesin: a competitive inhibitor of tyrosinase: K. Jones, et al.; Pigment Cell Res.
15, 335 (2002),
Abstract;
Mushroom tyrosinase inhibition activity of some chromones: L.Z. Piao, et al.; Chem. Pharm. Bull. (Tokyo)
50, 309 (2002),
Abstract;
Aloesin up-regulates cyclin E/CDK2 kinase activity via inducing the protein levels of cyclin E, CDK2, and CDC25A in SK-HEP-1 cells: K.Y. Lee, et al.; Biochem. Mol. Biol. Int.
41, 285 (1997),
Abstract;
Chromones in aloe species. I. Aloesin--a C-glucosyl-7-hydroxychromone: D.K. Holdsworth; Planta Med.
19, 322 (1971),
Abstract;
The distribution of aloesin in some South African Aloe species: T.J. McCarthy & L.J. Haynes; Planta Med.
15, 342 (1967),
Abstract;
