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Isobavachalcone

MMP-2 inhibitor
 
ALX-350-145-M001 1 mg 228.00 USD
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Inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Shows antifungal activity.

Product Specification

Alternative Name:2’,4’,4-Trihydroxy-3’-[3’’-methylbut-3’’-enyl]chalcone
 
Formula:C20H20O4
 
MW:324.4
 
Source:Isolated from plant Psoralea corylifolia.
 
CAS:20784-50-3
 
Purity:≥97% (HPLC)
 
Identity:Determined by 1H-NMR and MS.
 
Appearance:Yellow oil.
 
Solubility:Soluble in DMSO or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
350-145
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350-145

Product Literature References

Bavachin and isobavachalcone, acyl-coenzyme A: cholesterol acyltransferase inhibitors from Psoralea corylifolia: J.H. Choi et al.; Arch. Pharm. Res. 31, 1419 (2008), Abstract;
Inhibition of matrix metalloproteinase-2 secretion by chalcones from the twigs of Dorstenia barteri Bureau.: B. Ngameni, et al.; Arkivoc ix, 91 (2007), Full Text
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects: T. Akihisa, et al.; J. Nat. Prod. 69, 38 (2006), Abstract;
Antitrichomonal and antioxidant activities of Dorstenia barteri and Dorstenia convexa: N.O. Omisore, et al.; Braz. J. Med. Biol. Res. 38, 1087 (2005), Abstract;
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells: K. Tabata, et al.; Biol. Pharm. Bull. 28, 1404 (2005), Abstract;
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects: T. Akihisa, et al.; Cancer Lett. 201, 133 (2003), Abstract;
Antioxidative components of Psoralea corylifolia (Leguminosae): H. Haraguchi, et al.; Phytother. Res. 16, 539 (2002), Abstract;
Antiplatelet flavonoids from seeds of Psoralea corylifolia: W.J. Tsai, et al.; J. Nat. Prod. 59, 671 (1996), Abstract;

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