Aristoforin

SIRT inhibitor



ALX-350-129-M001	1 mg	186.00 USD

Stable and water-soluble derivative of hyperforin (Prod. No. ALX-350-097) inducing apoptosis. Antitumor agent. Inhibits sirtuins.

Product Specification

Identity:	Identity determined by MS, ¹H- and ¹³C-NMR.

Formula:	C₃₇H₅₄O₆

MW:	594.8

Purity:	≥95%

Appearance:	White to yellow oil.

CAS:	849215-53-8

Solubility:	Soluble in DMSO or 100mM sodium hydrogen carbonate/2% DMSO.

Long Term Storage:	-20°C

Hazard:	TOXIC.

Handling:	Protect from light.

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Product Literature References

Phloroglucinol Derivatives Guttiferone G, Aristoforin, and Hyperforin: Inhibitors of Human Sirtuins SIRT1 and SIRT2: C. Gey, et al.; Angew. Chem. Int. Ed. Engl. 46, 5219 (2007), Abstract;

Aristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent: M. Gartner, et al.; Chembiochem. 6, 171 (2005), Abstract;