Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 


Insulin sensitizing agent
ALX-350-125-M025 25 mg 119.00 USD
ALX-350-125-M100 100 mg 343.00 USD
Do you need bulk/larger quantities?
Potent insulin sensitizing agent. Peroxisome proliferator-activated receptor γ (PPAR-γ) agonist. Hepatotoxic. Antidiabetic.

Product Specification

MI:14: 8265
Purity:≥97% (HPLC)
Appearance:White to off-white solid.
Solubility:Soluble in DMSO (>25mg/ml), 100% ethanol or methanol.
Long Term Storage:+4°C
Use/Stability:Stable for 2 years after receipt when stored at +4°C. Stock solutions are stable for up to 3 months when stored at -20°C.
ALX-350-125 structure
Please mouse over
ALX-350-125 structure

Product Literature References

A PPAR-gamma agonist protects from radiation-induced intestinal toxicity: M. Mangoni, et al.; United European Gastroenterol. J. 5, 218 (2017), Application(s): Cell culture, Abstract; Full Text
A combination of (+)-catechin and (-)-epicatechin underlies the in vitro adipogenic action of Labrador tea (Rhododendron groenlandicum), an antidiabetic medicinal plant of the Eastern James Bay Cree pharmacopeia: H.M. Eid, et al. ; J. Ethnopharmacol. 178, 251 (2016), Application(s): Cell culture, Abstract;
ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs: M.H. Lee, et al.; Sci. Rep. 6, 21173 (2016), Application(s): Cell culture, Abstract; Full Text
Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma: H.Y. Lee, et al.; Korean J. Intern. Med. 31, 89 (2016), Application(s): Cell culture, Abstract; Full Text
Effects of alpha-lipoic acid on chemerin secretion in 3 T3-L1 and human adipocytes: P.L. Prieto-Hontoria, et al. ; Biochim. Biophys. Acta 1861, 260 (2016), Application(s): Cell culture, Abstract;
A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice: Y. Shiomi, et al.; J. Biol. Chem. 290, 14567 (2015), Application(s): Cell Culture, Abstract; Full Text
Expression of human and mouse adenine nucleotide translocase (ANT) isoform genes in adipogenesis: A. Gavaldà-Navarro, et al.; Int. J. Biochem. Cell. Biol. 64, 34 (2015), Application(s): Cell Culture, Abstract;
Rosiglitzone Suppresses Angiotensin II-Induced Production of KLF5 and Cell Proliferation in Rat Vascular Smooth Muscle Cells: D. Gao, et al.; PLoS One 10, e0123724 (2015), Application(s): Cell Culture, Abstract; Full Text
Modulation of RAGE and the Downstream Targets of RAGE Signaling Cascades by Taurine in Lycium Barbarum (Goji Berry): Protection of Human Retinal Pigment Epithelial Barrier Function and its Potential Benefit in Diabetic Retinopathy: M.K. Song, et al.; J. Diabetes Metab. 2, 162 (2011), Application(s): Cell Culture, Full Text
A review of rosiglitazone in type 2 diabetes mellitus: A.L. Werner & M.T. Travaglini; Pharmacotherapy 21, 1082 (2001), (Review), Abstract;
Rosiglitazone (Avandia): hepatic, cardiac and hematological reactions: M. McMorran & D. Vu; CMAJ 165, 82 (2001), Abstract;
Rosiglitazone in the treatment of type 2 diabetes mellitus: a critical review: J.M. Malinowski & S. Bolesta; Clin. Ther. 22, 1151 (2000), (Review), Abstract;
Rosiglitazone: an agent from the thiazolidinedione class for the treatment of type 2 diabetes: A. Cheng-Lai & A. Levine; Heart Dis. 2, 326 (2000), (Review), Abstract;
Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes: G.A. Knock, et al.; Eur. J. Pharmacol. 368, 103 (1999), Abstract;
Rosiglitazone: J.A. Balfour & G.L. Plosker; Drugs 57, 921 (1999), (Review) , Abstract;
Differential activity of rosiglitazone enantiomers at PPAR gamma: D.J. Parks, et al.; Bioorg. Med. Chem. Lett. 81, 3657 (1998), Abstract;

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
PPAR Ligand
PPAR Activator
By catalog section:


Technical Service
Customer Service

Related Literature

Diabetes Catalog
Diabetes Catalog
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,