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Anabasine . hydrochloride

Acetylcholine receptor activator
ALX-350-112-M025 25 mg 13.00 USD
ALX-350-112-M100 100 mg 42.00 USD
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Tobacco alkaloid. Potent nicotinic acetylcholine receptor agonist. Insecticide.

Product Specification

Alternative Name:3-(2-Piperidinyl)pyridine, 2-(3-Pyridyl)piperidine, Neonicotine
Formula:C10H14N2 . HCl
MW:162.2 . 36.5
Source:Isolated from Anabasis aphylla.
MI:14: 619
Purity:≥97% (TLC, NMR)
Appearance:White to off-white solid.
Solubility:Soluble in alcohol or water.
Long Term Storage:+4°C
Handling:Protect from light.
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Product Literature References

Anabasine toxicity from a topical folk remedy: N.G. Murphy, et al.; Clin. Pediatr. (Phila) 45, 669 (2006), Abstract;
Anabasine, a selective nicotinic acetylcholine receptor agonist, antagonizes MK-801-elicited mouse popping behavior, an animal model of schizophrenia: J. Mastropaolo, et al.; Behav. Brain Res. 153, 419 (2004), Abstract;
Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry: X. Xu, et al.; Clin. Chem. 50, 2323 (2004), Abstract;
Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy: P. Jacob, 3rd, et al.; Cancer Epidemiol. Biomarkers Prev. 11, 1668 (2002), Abstract;
Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro: R.L. Barbieri, et al.; J. Clin. Invest. 77, 1727 (1986), Abstract;

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