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Sibutramine . hydrochloride . monohydrate

Anti-obesity agent
 
ALX-350-111-G001 1 g 72.00 USD
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Anti-obesity agent. Prevents resorption of the messenger substances serotonin and noradrenalin in the brain, allowing them to act at higher concentration on nerve cells and increasing the feeling of satiety.

Product Specification

Alternative Name:1-(4-Chlorophenyl-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine . HCl . H2O
 
Formula:C17H26ClN . HCl . H2O
 
MW:279.9 . 36.5 . 18.0
 
CAS:125494-59-9
 
MI:14: 8485
 
Purity:≥98% (Assay)
 
Appearance:White to off-white crystalline powder.
 
MeltingPoint:190-201°C
 
Solubility:Soluble in methanol or water (2.9mg/ml at pH 5.2).
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
350-111
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350-111

Product Literature References

A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models: Y. Kawata, et al.; Eur. J. Pharmacol. 796, 45 (2016), Abstract;

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