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Nidulal

 
ALX-350-110-MC05 0.5 mg 126.00 USD
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Induces differentiation of human HL-60 promyelocytic leukemia cells.
Activates the transcription factor complex AP-1 -mediated expression of secreted alkaline phosphatase in COS-7 cells.

Product Specification

Alternative Name:4-(8-methyl-4,7-dioxo-1,6-dioxaspiro[4.4]nona-2,8-dien-3-yl)cyclohexanecarbaldehyde
 
Formula:C15H16O5
 
MW:276.3
 
Source:Isolated from Nidula candida.
 
CAS:185853-14-9
 
Purity:≥95%
 
Appearance:Lyophilized
 
Solubility:Soluble in 100% ethanol, methanol or DMSO.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Handling:Protect from light. Keep cool and dry. After reconstitution, prepare aliquots and store at -20°C.
 
350-110
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350-110

Product Literature References

Quantifying biogenic bias in screening libraries: J. Hert, et al.; Nat. Chem. Biol. 5, 479 (2009), Abstract;
Nidulal, a novel inducer of differentiation of human promyelocytic leukemia cells from Nidula candida: G. Erkel, et al.; J. Antibiot. 49, 1189 (1996), Abstract; Full Text

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