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Lavendustin C methyl ester

EGFR inhibitor with improved bioavailability
 
ALX-350-084-M005 5 mg 137.00 USD
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Inhibitor of EGFR tyrosine kinase with improved bioavailability over lavendustin C (Prod. No. BML-EI232).

Product Specification

Alternative Name:Compound 5 methyl ester, 5-Amino-N-(2,5-dihydroxybenzyl)methyl salicylate
 
Formula:C15H15NO5
 
MW:289.3
 
Source:Synthetic.
 
Purity:≥97%
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-350-084
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ALX-350-084

Product Literature References

Structure-activity relationships in a series of 5-[(2,5- dihydroxybenzyl)amino]salicylate inhibitors of EGF-receptor-associated tyrosine kinase: importance of additional hydrophobic aromatic interactions: H. Chen, et al.; J. Med. Chem. 37, 845 (1994), Abstract;
Synthesis and structure-activity studies of a series of [(hydroxybenzyl)amino]salicylates as inhibitors of EGF receptor- associated tyrosine kinase activity: H. Chen, et al.; J. Med. Chem. 36, 4094 (1993), Abstract;

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